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ERK2, but not ERK1, induces epithelial to mesenchymal transformation via DEF motif dependent signaling events
Hyperactivation of Ras-ERK1/2 signaling is critical to the development of many human malignancies but little is known regarding the specific contribution of ERK1 or ERK2 to oncogenic processes. We demonstrate that ERK2 but not ERK1 signaling is necessary for Ras-induced epithelial-to-mesenchymal tra...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854677/ https://ncbi.nlm.nih.gov/pubmed/20385094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.020 |
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