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Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity

Slit–Roundabout (Robo) signalling has a well-understood role in axon guidance1–5. Unlike in the nervous system, however, Slitdependent activation of an endothelial-specific Robo, Robo4, does not initiate a guidance program. Instead, Robo4 maintains the barrier function of the mature vascular network...

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Detalhes bibliográficos
Main Authors: Jones, Christopher A., Nishiya, Naoyuki, London, Nyall R., Zhu, Weiquan, Sorensen, Lise K., Chan, Aubrey C., Lim, Chinten J., Chen, Haoyu, Zhang, Qisheng, Schultz, Peter G., Hayallah, Alaa M., Thomas, Kirk R., Famulok, Michael, Zhang, Kang, Ginsberg, Mark H., Li, Dean Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854659/
https://ncbi.nlm.nih.gov/pubmed/19855388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1976
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