Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity

Slit–Roundabout (Robo) signalling has a well-understood role in axon guidance1–5. Unlike in the nervous system, however, Slitdependent activation of an endothelial-specific Robo, Robo4, does not initiate a guidance program. Instead, Robo4 maintains the barrier function of the mature vascular network...

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Bibliografiset tiedot
Päätekijät: Jones, Christopher A., Nishiya, Naoyuki, London, Nyall R., Zhu, Weiquan, Sorensen, Lise K., Chan, Aubrey C., Lim, Chinten J., Chen, Haoyu, Zhang, Qisheng, Schultz, Peter G., Hayallah, Alaa M., Thomas, Kirk R., Famulok, Michael, Zhang, Kang, Ginsberg, Mark H., Li, Dean Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854659/
https://ncbi.nlm.nih.gov/pubmed/19855388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1976
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