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Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity
Slit–Roundabout (Robo) signalling has a well-understood role in axon guidance1–5. Unlike in the nervous system, however, Slitdependent activation of an endothelial-specific Robo, Robo4, does not initiate a guidance program. Instead, Robo4 maintains the barrier function of the mature vascular network...
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Main Authors: | , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854659/ https://ncbi.nlm.nih.gov/pubmed/19855388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1976 |
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