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Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability

Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial permeability to foster dissemination, but the mechanism is largely unexplored. Using a primary human lymphatic endothelial cell model, we foun...

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Detalhes bibliográficos
Main Authors: Zhang, Xuefeng, Yu, Jinlong, Kuzontkoski, Paula M., Zhu, Weiquan, Li, Dean Y., Groopman, Jerome E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252370/
https://ncbi.nlm.nih.gov/pubmed/22241990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002461
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