Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway

BACKGROUND: Signaling through vascular endothelial growth factor C (VEGF–C) and VEGF receptor 3 (VEGFR-3) plays a central role in lymphangiogenesis and the metastasis of several cancers via the lymphatics. Recently, the Slit2/Robo4 pathway has been recognized as a modulator of vascular permeability...

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Detalhes bibliográficos
Main Authors: Yu, Jinlong, Zhang, Xuefeng, Kuzontkoski, Paula M, Jiang, Shuxian, Zhu, Weiquan, Li, Dean Y, Groopman, Jerome E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122147/
https://ncbi.nlm.nih.gov/pubmed/24708522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-25
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