Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

The angiogenic sprout has been compared to the growing axon, and indeed, many proteins direct pathfinding by both structures1. The Roundabout (Robo) proteins are guidance receptors with well-established functions in the nervous system2,3; however, their role in the mammalian vasculature remains ill...

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Detalhes bibliográficos
Main Authors: Jones, Christopher A, London, Nyall R, Chen, Haoyu, Won Park, Kye, Sauvaget, Dominique, Stockton, Rebecca A, Wythe, Joshua D, Suh, Wonhee, Larrieu-Lahargue, Frederic, Mukouyama, Yoh-suke, Lindblom, Per, Seth, Pankaj, Frias, Antonio, Nishiya, Naoyuki, Ginsberg, Mark H, Gerhardt, Holger, Zhang, Kang, Li, Dean Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875252/
https://ncbi.nlm.nih.gov/pubmed/18345009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1742
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