The ribosome-bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex

Bacterial translation initiation factor 2 (IF2) is a GTPase that promotes the binding of the initiator fMet-tRNA(fMet) to the 30S ribosomal subunit. It is often assumed that IF2 delivers fMet-tRNA(fMet) to the ribosome in a ternary complex, IF2·GTP·fMet-tRNA(fMet). By using rapid kinetic techniques,...

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Autors principals: Milon, Pohl, Carotti, Marcello, Konevega, Andrey L, Wintermeyer, Wolfgang, Rodnina, Marina V, Gualerzi, Claudio O
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Scientific Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854590/
https://ncbi.nlm.nih.gov/pubmed/20224578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.12
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