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Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome.
The fidelity of aminoacyl-tRNA (aa-tRNA) selection by the bacterial ribosome is determined by initial selection before and proofreading after GTP hydrolysis by elongation factor Tu. Here we report the rate constants of A-site binding of a near-cognate aa-tRNA. The comparison with the data for cognat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171457/ https://ncbi.nlm.nih.gov/pubmed/10393195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.13.3800 |
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