On the evolution of accuracy and cost of proofreading tRNA aminoacylation.
Aminoacylation of tRNA occurs with a high degree of accuracy in many cases because misacylated molecules are effectively proofread on the aminoacyl-tRNA synthetase by preferential hydrolysis. This hydrolysis releases an ATP equivalent of energy. An explicit relationship between cost of proofreading...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1979
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/388443/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4507 |
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