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Experimental evidence for kinetic proofreading in the aminoacylation of tRNA by synthetase.

The enzymatic aminoacylation of tRNA can be viewed as a means of proofreading either the amino acid or the tRNA or both. We have conducted further experimental tests of kinetic proofreading in discriminating between cognate and noncognate amino acids and tRNAs as follows: (formula: see text). In cas...

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Detalhes bibliográficos
Main Authors: Yamane, T, Hopfield, J J
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC432146/
https://ncbi.nlm.nih.gov/pubmed/329276
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