Experimental evidence for kinetic proofreading in the aminoacylation of tRNA by synthetase.
The enzymatic aminoacylation of tRNA can be viewed as a means of proofreading either the amino acid or the tRNA or both. We have conducted further experimental tests of kinetic proofreading in discriminating between cognate and noncognate amino acids and tRNAs as follows: (formula: see text). In cas...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1977
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/329276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.6.2246 |
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