WSTF regulates the function of H2A.X via a novel tyrosine kinase activity

DNA double-stranded breaks present a serious challenge for eukaryotic cells. Inability to repair breaks leads to genomic instability, carcinogenesis, and cell death. During the DSB response, mammalian chromatin undergoes reorganization demarcated by H2A.X Ser139 phosphorylation (γ-H2A.X). However, t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xiao, Andrew, Li, Haitao, Shechter, David, Ahn, Sung Hee, Fabrizio, Laura A., Erdjument-Bromage, Hediye, Ishibe-Murakami, Satoko, Wang, Bin, Tempst, Paul, Hofmann, Kay, Patel, Dinshaw J., Elledge, Stephen J., Allis, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854499/
https://ncbi.nlm.nih.gov/pubmed/19092802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07668
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados