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Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch

Tetrahydrofolate (THF), a biologically active form of the vitamin folate (B(9)), is an essential cofactor in one-carbon transfer reactions. In bacteria, expression of folate-related genes is controlled by feedback modulation in response to specific binding of THF and related compounds to a riboswitc...

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Detalhes bibliográficos
Main Authors: Huang, Lili, Ishibe-Murakami, Satoko, Patel, Dinshaw J., Serganov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169164/
https://ncbi.nlm.nih.gov/pubmed/21873197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111701108
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