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Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

Fluid shear stress generated by steady laminar blood flow protects vessels from atherosclerosis. Krüppel-like factor 2 (KLF2) and endothelial nitric oxide synthase (eNOS) are fluid shear stress–responsive genes and key mediators in flow anti-inflammatory and antiatherosclerotic actions. However, the...

詳細記述

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書誌詳細
主要な著者: Wang, Weiye, Ha, Chang Hoon, Jhun, Bong Sook, Wong, Chelsea, Jain, Mukesh K., Jin, Zheng-Gen
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854437/
https://ncbi.nlm.nih.gov/pubmed/20042720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-224824
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