Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation

Runx1 is required for the emergence of hematopoietic stem cells (HSCs) from hemogenic endothelium during embryogenesis. However, its role in the generation and maintenance of HSCs during adult hematopoiesis remains uncertain. Here, we present analysis of a zebrafish mutant line carrying a truncation...

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Detalhes bibliográficos
Main Authors: Sood, Raman, English, Milton A., Belele, Christiane L., Jin, Hao, Bishop, Kevin, Haskins, Rebecca, McKinney, Mary Cathleen, Chahal, Jagman, Weinstein, Brant M., Wen, Zilong, Liu, P. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854427/
https://ncbi.nlm.nih.gov/pubmed/20154212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236729
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