Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish

The transcription factor Gata1 is required for the development of erythrocytes and megakaryocytes. Previous studies with a complementation rescue approach showed that the zinc finger domains are required for both primitive and definitive hematopoiesis. Here we report a novel zebrafish gata1 mutant w...

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Detalhes bibliográficos
Main Authors: Belele, Christiane L., English, Milton A., Chahal, Jagman, Burnetti, Anthony, Finckbeiner, Steven M., Gibney, Gretchen, Kirby, Martha, Sood, Raman, Liu, P. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792212/
https://ncbi.nlm.nih.gov/pubmed/19843882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-224709
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