Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish

The transcription factor Gata1 is required for the development of erythrocytes and megakaryocytes. Previous studies with a complementation rescue approach showed that the zinc finger domains are required for both primitive and definitive hematopoiesis. Here we report a novel zebrafish gata1 mutant w...

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Главные авторы: Belele, Christiane L., English, Milton A., Chahal, Jagman, Burnetti, Anthony, Finckbeiner, Steven M., Gibney, Gretchen, Kirby, Martha, Sood, Raman, Liu, P. Paul
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2009
Предметы:
Hematopoiesis and Stem Cells
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792212/
https://ncbi.nlm.nih.gov/pubmed/19843882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-224709
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