Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology

During myofibril assembly, thin filament lengths are precisely specified to optimize skeletal muscle function. Tropomodulins (Tmods) are capping proteins that specify thin filament lengths by controlling actin dynamics at pointed ends. In this study, we use a genetic targeting approach to explore th...

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Hlavní autoři: Gokhin, David S., Lewis, Raymond A., McKeown, Caroline R., Nowak, Roberta B., Kim, Nancy E., Littlefield, Ryan S., Lieber, Richard L., Fowler, Velia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854367/
https://ncbi.nlm.nih.gov/pubmed/20368620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001125
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