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Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers

In skeletal muscle, thick and thin filaments are arranged in a myofibrillar lattice. Tropomodulin 1 (Tmod1) is a pointed-end capping and tropomyosin-binding protein that controls thin-filament assembly, stability, and lengths. It remains unknown whether Tmods have other functional roles, such as reg...

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Main Authors: Ochala, Julien, Gokhin, David S., Iwamoto, Hiroyuki, Fowler, Velia M.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868837/
https://ncbi.nlm.nih.gov/pubmed/24072783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-239640
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