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Cytoplasmic γ-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers

The sarcoplasmic reticulum (SR) serves as the Ca(2+) reservoir for muscle contraction. Tropomodulins (Tmods) cap filamentous actin (F-actin) pointed ends, bind tropomyosins (Tms), and regulate F-actin organization. In this paper, we use a genetic targeting approach to examine the effect of Tmod1 del...

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Detalhes bibliográficos
Main Authors: Gokhin, David S., Fowler, Velia M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135406/
https://ncbi.nlm.nih.gov/pubmed/21727195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011128
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