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Effects of the mGlu2/3 Agonist LY379268 and the mGlu5 Antagonist MTEP on Ethanol-Seeking and Reinforcement are Differentially Altered in Rats with a History of Ethanol Dependence
BACKGROUND: Growing evidence supports a role of metabotropic glutamate receptors (mGluRs) in ethanol reinforcement, ethanol-seeking, and ethanol withdrawal. To extend the understanding of the role of mGluRs in the addiction-relevant effects of ethanol as well as of the treatment target potential of...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854322/ https://ncbi.nlm.nih.gov/pubmed/20189165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.01.005 |
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