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Effects of the mGlu2/3 Agonist LY379268 and the mGlu5 Antagonist MTEP on Ethanol-Seeking and Reinforcement are Differentially Altered in Rats with a History of Ethanol Dependence

BACKGROUND: Growing evidence supports a role of metabotropic glutamate receptors (mGluRs) in ethanol reinforcement, ethanol-seeking, and ethanol withdrawal. To extend the understanding of the role of mGluRs in the addiction-relevant effects of ethanol as well as of the treatment target potential of...

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Detalhes bibliográficos
Main Authors: Sidhpura, Nimish, Weiss, Friedbert, Martin-Fardon, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854322/
https://ncbi.nlm.nih.gov/pubmed/20189165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.01.005
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