Enhanced Sensitivity to Attenuation of Conditioned Reinstatement by the mGluR(2/3) Agonist LY379268 and Increased Functional Activity of mGluR(2/3) in Rats with a History of Ethanol Dependence

Recent findings implicate group II metabotropic glutamate receptors (mGluR(2/3)) in the reinforcing and dependence-inducing actions of ethanol and identify these receptors as treatment targets for alcoholism. Here, we investigated the effects of mGLuR(2/3) activation on conditioned reinstatement in...

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Bibliographic Details
Main Authors: Kufahl, Peter R, Martin-Fardon, Rémi, Weiss, Friedbert
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230501/
https://ncbi.nlm.nih.gov/pubmed/21881571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.174
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