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Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo

1. Previous studies investigating the role of metabotropic glutamate (mGlu) receptors in nociceptive processing have been hampered by the lack of systemically active, selective, ligands. This study investigates the possible analgesic and/or anti-hyperalgesic properties of the most potent compound to...

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Detalhes bibliográficos
Main Authors: Sharpe, E F, Kingston, A E, Lodge, D, Monn, J A, Headley, P M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573247/
https://ncbi.nlm.nih.gov/pubmed/11877334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704583
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