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Possible involvement of Toll-Like Receptor 4/MD-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences

Opioid-induced glial activation and its proinflammatory consequences have been associated with both reduced acute opioid analgesia and the enhanced development of tolerance, hyperalgesia and allodynia following chronic opioid administration. Intriguingly, recent evidence demonstrates that these effe...

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書誌詳細
主要な著者: Hutchinson, Mark R., Lewis, Susannah S., Coats, Benjamen D., Rezvani, Niloofar, Zhang, Yingning, Wieseler, Julie L., Somogyi, Andrew A., Yin, Hang, Maier, Steven F., Rice, Kenner C., Watkins, Linda R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854318/
https://ncbi.nlm.nih.gov/pubmed/20178837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.02.011
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