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Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA(−/−)) mice

Tissue Plasminogen Activator (tPA) is a serine protease expressed in different areas of the mammalian brain. It has been used clinically to dissolve clots and shown to have a role in neurodegeneration. Early studies suggested that tPA plays an important role in the processes of learning and memory,...

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Autori principali: Pothakos, Konstantinos, Robinson, John K., Gravanis, Iordanis, Marsteller, Douglas A., Dewey, Stephen L., Tsirka, Stella E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853966/
https://ncbi.nlm.nih.gov/pubmed/20156421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.12.095
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