Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

Simultaneous ablation of the two known activators of plasminogen (Plg), urokinase-type (uPA) and the tissue-type (tPA), results in a substantial delay in skin wound healing. However, wound closure and epidermal re-epithelialization are significantly less impaired in uPA;tPA double-deficient mice tha...

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Detalhes bibliográficos
Main Authors: Lund, Leif R, Green, Kirsty A, Stoop, Allart A, Ploug, Michael, Almholt, Kasper, Lilla, Jennifer, Nielsen, Boye S, Christensen, Ib J, Craik, Charles S, Werb, Zena, Danø, Keld, Rømer, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500865/
https://ncbi.nlm.nih.gov/pubmed/16763560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601173
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