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Axonal Regrowth after Spinal Cord Injury via Chondroitinase and the Tissue Plasminogen Activator (tPA)/Plasmin System

Spinal cord injury (SCI) causes permanent debilitation due to the inability of axons to grow through established scars. Both the sugar chains and core proteins of chondroitin sulfate proteoglycans (CSPGs) are inhibitory for neurite regrowth. Chondroitinase ABC (ChABC) degrades the sugar chains and a...

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Autors principals: Bukhari, Noreen, Torres, Luisa, Robinson, John K., Tsirka, Stella E.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206287/
https://ncbi.nlm.nih.gov/pubmed/22016526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3339-11.2011
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