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Axonal Regrowth after Spinal Cord Injury via Chondroitinase and the Tissue Plasminogen Activator (tPA)/Plasmin System
Spinal cord injury (SCI) causes permanent debilitation due to the inability of axons to grow through established scars. Both the sugar chains and core proteins of chondroitin sulfate proteoglycans (CSPGs) are inhibitory for neurite regrowth. Chondroitinase ABC (ChABC) degrades the sugar chains and a...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206287/ https://ncbi.nlm.nih.gov/pubmed/22016526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3339-11.2011 |
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