Oligomer-Specific Conformations of the Human Immunodeficiency Virus (HIV-1) gp41 Envelope Glycoprotein Ectodomain Recognized by Human Monoclonal Antibodies

Trimerization of the human immunodeficiency virus (HIV-1) envelope glycoproteins is mediated by the ectodomain of the gp41 transmembrane glycoprotein. Here we investigate oligomer-specific conformations of gp41 by using monoclonal antibodies (MAbs) from HIV-1-infected humans. Human MAbs directed aga...

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Bibliographic Details
Main Authors: Yuan, Wen, Li, Xing, Kasterka, Marta, Gorny, Miroslaw K., Zolla-Pazner, Susan, Sodroski, Joseph
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2009
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853836/
https://ncbi.nlm.nih.gov/pubmed/19292593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0213
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