Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly

Niemann-Pick C1-like 1 protein (NPC1L1) plays a critical role in intestinal cholesterol absorption. Our objective was to examine whether five variants (-133A>G, -18A>C, L272L, V1296V, and U3_28650A>G) at the NPC1L1 gene have effects on lipid levels, prevalence, and incidence of coronary hea...

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Autori principali: Polisecki, Eliana, Peter, Inga, Simon, Jason S., Hegele, Robert A., Robertson, Michele, Ford, Ian, Shepherd, James, Packard, Christopher, Jukema, J. Wouter, de Craen, Anton J. M., Westendorp, Rudi G. J., Buckley, Brendan M., Schaefer, Ernst J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Patient-Oriented and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853447/
https://ncbi.nlm.nih.gov/pubmed/19752398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P001172
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