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Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge
Farnesoid X receptor (FXR) is a nuclear receptor that regulates genes involved in synthesis, metabolism, and transport of bile acids and thus plays a major role in maintaining bile acid homeostasis. In this study, metabolomic responses were investigated in urine of wild-type and Fxr-null mice fed ch...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Biochemistry and Molecular Biology
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853433/ https://ncbi.nlm.nih.gov/pubmed/19965603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002923 |
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