Isoflurane via TGF-β1 release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubules

We previously showed that the inhalational anesthetic isoflurane protects against renal proximal tubule necrosis via isoflurane-mediated stimulation and translocation of sphingosine kinase-1 (SK1) with subsequent synthesis of sphingosine-1-phosphate (S1P) in renal proximal tubule cells (Kim M, Kim M...

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Detalhes bibliográficos
Main Authors: Song, Joseph H., Kim, Mihwa, Park, Sang Won, Chen, Sean W. C., Pitson, Stuart M., Lee, H. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853319/
https://ncbi.nlm.nih.gov/pubmed/20053797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00115.2009
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