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Isoflurane via TGF-β1 release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubules
We previously showed that the inhalational anesthetic isoflurane protects against renal proximal tubule necrosis via isoflurane-mediated stimulation and translocation of sphingosine kinase-1 (SK1) with subsequent synthesis of sphingosine-1-phosphate (S1P) in renal proximal tubule cells (Kim M, Kim M...
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Huvudupphovsmän: | , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
American Physiological Society
2010
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853319/ https://ncbi.nlm.nih.gov/pubmed/20053797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00115.2009 |
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