Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia

Renal ischemia reperfusion injury is a major cause of acute kidney injury. We previously found that renal A1 adenosine receptor (A1AR) activation attenuated multiple cell death pathways including necrosis, apoptosis and inflammation. Here, we tested whether induction of cytoprotective sphingosine ki...

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Detalhes bibliográficos
Main Authors: Park, Sang Won, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Haase, Volker H., D’Agati, Vivette D., Lee, H. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443517/
https://ncbi.nlm.nih.gov/pubmed/22695326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.224
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