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Inhibition of Sphingosine 1-Phosphate Receptor 2 Protects against Renal Ischemia-Reperfusion Injury

Activation of the sphingosine 1-phosphate receptor 1 (S1P(1)R) protects against renal ischemia-reperfusion (IR) injury and inflammation, but the role of other members of this receptor family in modulating renal IR injury is unknown. We found that a selective S1P(2)R antagonist protected against rena...

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Autors principals: Won Park, Sang, Kim, Mihwa, Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269189/
https://ncbi.nlm.nih.gov/pubmed/22095950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050503
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