A(1) adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury

Activation of A(1) adenosine receptors (ARs) protects against renal ischemia-reperfusion (I/R) injury by reducing necrosis, apoptosis, and inflammation. However, extrarenal side effects (bradycardia, hypotension, and sedation) may limit A(1)AR agonist therapy for ischemic acute kidney injury. Here,...

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Autors principals: Park, Sang Won, Kim, Joo Yun, Ham, Ahrom, Brown, Kevin M., Kim, Mihwa, D'Agati, Vivette D., Lee, H. Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468496/
https://ncbi.nlm.nih.gov/pubmed/22759398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00157.2012
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