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A(1) adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury
Activation of A(1) adenosine receptors (ARs) protects against renal ischemia-reperfusion (I/R) injury by reducing necrosis, apoptosis, and inflammation. However, extrarenal side effects (bradycardia, hypotension, and sedation) may limit A(1)AR agonist therapy for ischemic acute kidney injury. Here,...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468496/ https://ncbi.nlm.nih.gov/pubmed/22759398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00157.2012 |
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