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miR-221 suppresses ICAM-1 translation and regulates interferon-γ-induced ICAM-1 expression in human cholangiocytes

Aberrant cholangiocyte reactions in response to inflammatory stimuli are important pathogenic factors for the persistent biliary inflammation in patients with cholangiopathies. Overexpression of intercellular cell adhesion molecule-1 (ICAM-1) in cholangiocytes is a common pathological feature in inf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hu, Guoku, Gong, Ai-Yu, Liu, Jun, Zhou, Rui, Deng, Caishu, Chen, Xian-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853302/
https://ncbi.nlm.nih.gov/pubmed/20110463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00490.2009
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