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Hierarchical clustering of immunohistochemical analysis of the activated ErbB/PI3K/Akt/NF-κB signalling pathway and prognostic significance in prostate cancer

BACKGROUND: The PI3K/Akt signalling pathway, induced by epidermal growth factor receptor (EGFR) and Her-2, is involved in the constitutive activation of NF-κB in prostate cancer cell lines. In this study, we extended the in vitro observation using an ex vivo model of prostate cancer tissues and asse...

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Main Authors: Koumakpayi, I H, Le Page, C, Mes-Masson, A-M, Saad, F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853085/
https://ncbi.nlm.nih.gov/pubmed/20216540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605571
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