NF-κB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation

Activation of NF-κB in inflammatory breast cancer (IBC) is associated with loss of estrogen receptor (ER) expression, indicating a potential crosstalk between NF-κB and ER. In this study, we examined the activation of NF-κB in IBC and non-IBC with respect to ER and EGFR and/or ErbB2 expression and M...

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Detalhes bibliográficos
Main Authors: Van Laere, S J, Van der Auwera, I, Van den Eynden, G G, van Dam, P, Van Marck, E A, Vermeulen, P B, Dirix, L Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360371/
https://ncbi.nlm.nih.gov/pubmed/17700572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603906
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