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Topological Analysis of MAPK Cascade for Kinetic ErbB Signaling

Ligand-induced homo- and hetero-dimer formation of ErbB receptors results in different biological outcomes irrespective of recruitment and activation of similar effector proteins. Earlier experimental research indicated that cells expressing both EGFR (epidermal growth factor receptor) and the ErbB4...

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Main Authors: Nakakuki, Takashi, Yumoto, Noriko, Naka, Takashi, Shirouzu, Mikako, Yokoyama, Shigeyuki, Hatakeyama, Mariko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262155/
https://ncbi.nlm.nih.gov/pubmed/18335053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001782
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