A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling.

ErbB tyrosine kinase receptors mediate mitogenic signal cascade by binding a variety of ligands and recruiting the different cassettes of adaptor proteins. In the present study, we examined heregulin (HRG)-induced signal transduction of ErbB4 receptor and found that the phosphatidylinositol 3'-...

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Detalhes bibliográficos
Main Authors: Hatakeyama, Mariko, Kimura, Shuhei, Naka, Takashi, Kawasaki, Takuji, Yumoto, Noriko, Ichikawa, Mio, Kim, Jae-Hoon, Saito, Kazuki, Saeki, Mihoro, Shirouzu, Mikako, Yokoyama, Shigeyuki, Konagaya, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223496/
https://ncbi.nlm.nih.gov/pubmed/12691603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021824
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