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β-Peptides as inhibitors of protein–protein interactions

We became interested several years ago in exploring whether 14-helical β-peptide foldamers could bind protein surfaces and inhibit protein–protein interactions, and if so, whether their affinities and specificities would compare favorably with those of natural or miniature proteins. This exploration...

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Bibliographic Details
Main Authors: Kritzer, Joshua A., Stephens, Olen M., Guarracino, Danielle A., Reznik, Samuel K., Schepartz, Alanna
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853017/
https://ncbi.nlm.nih.gov/pubmed/15582447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2004.09.009
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