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β-Peptides as inhibitors of protein–protein interactions

We became interested several years ago in exploring whether 14-helical β-peptide foldamers could bind protein surfaces and inhibit protein–protein interactions, and if so, whether their affinities and specificities would compare favorably with those of natural or miniature proteins. This exploration...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kritzer, Joshua A., Stephens, Olen M., Guarracino, Danielle A., Reznik, Samuel K., Schepartz, Alanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853017/
https://ncbi.nlm.nih.gov/pubmed/15582447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2004.09.009
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