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β-Peptides with improved affinity for hDM2 and hDMX
We previously described a series of 3(14)-helical β-peptides that bind the hDM2 protein and inhibit its interaction with a p53-derived peptide in vitro. Here we present a detailed characterization of the interaction of these peptides with hDM2 and report two new β-peptides in which non-natural side...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926950/ https://ncbi.nlm.nih.gov/pubmed/19211253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.01.039 |
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