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Bridged β(3)-Peptide Inhibitors of p53-hDM2 Complexation–Correlation Between Affinity and Cell Permeability
β-peptides possess several features that are desirable in peptidomimetics; they are easily synthesized, fold into stable secondary structures in physiologic buffers, and resist proteolysis. They can also bind to a diverse array of proteins to inhibit their interactions with α–helical ligands. β–pept...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853015/ https://ncbi.nlm.nih.gov/pubmed/20158215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910715u |
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