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Bridged β(3)-Peptide Inhibitors of p53-hDM2 Complexation–Correlation Between Affinity and Cell Permeability
β-peptides possess several features that are desirable in peptidomimetics; they are easily synthesized, fold into stable secondary structures in physiologic buffers, and resist proteolysis. They can also bind to a diverse array of proteins to inhibit their interactions with α–helical ligands. β–pept...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853015/ https://ncbi.nlm.nih.gov/pubmed/20158215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910715u |
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