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In silico improvement of β(3)-peptide inhibitors of p53•hDM2 and p53•hDMX
There is great interest in molecules capable of inhibiting the interactions between p53 and its negative regulators hDM2 and hDMX, as these molecules have validated potential against cancers in which one or both oncoproteins are overexpressed. We reported previously that appropriately substituted β(...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754742/ https://ncbi.nlm.nih.gov/pubmed/19415930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja901478e |
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