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KINETIC ANALYSIS OF B/HLH/Z TRANSCRIPTION FACTORS MYC, MAX AND MAD INTERACTION WITH COGNATE DNA

Myc, Mad and Max proteins belong to the basic helix-loop-helix leucine zipper family of transcription factors. They bind to a specific hexanucleotide element of DNA, the E-box (CACGTG). In order to be biologically active, Myc and Mad require dimerization with Max. For the route of complex assembly o...

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Main Authors: Ecevit, Ozgur, Khan, Mateen A, Goss, Dixie J
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852888/
https://ncbi.nlm.nih.gov/pubmed/20170194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901913a
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