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Thermodynamics of Protein–Protein Interactions of cMyc, Max, and Mad: Effect of Polyions on Protein Dimerization

The Myc–Max–Mad network of proteins activates or represses gene transcription depending on whether the dimerization partner of Max is c-Myc or Mad. To elucidate the physical properties of these protein–protein interactions, fluorescence anisotropy of TRITC-labeled Max was used. The binding affinitie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Banerjee, Anamika, Hu, Jianzhong, Goss, Dixie J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915447/
https://ncbi.nlm.nih.gov/pubmed/16475822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0522551
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