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Assembly of b/HLH/z proteins cMyc, Max and Mad1 with Cognate DNA: Importance of Protein-Protein and Protein-DNA Interactions

Among the best characterized of the transcription factors are the b/HLH/z proteins: USF, Max, Myc and Mad. These proteins bind to the DNA E-box, a six base pair sequence, CACGTG. Max and Myc form a heterodimer that has strong oncogenic potential but can also repress transcription, while Mad and Max...

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Détails bibliographiques
Auteurs principaux: Hu, Jianzhong, Banerjee, Anamika, Goss, Dixie J.
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225066/
https://ncbi.nlm.nih.gov/pubmed/16128587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050206i
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