Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.

The basic helix-loop-helix-leucine zipper (bHLHZip) protein Max associates with members of the Myc family, as well as with the related proteins Mad (Mad1) and Mxi1. Whereas both Myc:Max and Mad:Max heterodimers bind related E-box sequences, Myc:Max activates transcription and promotes proliferation...

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Detalhes bibliográficos
Main Authors: Hurlin, P J, Quéva, C, Koskinen, P J, Steingrímsson, E, Ayer, D E, Copeland, N G, Jenkins, N A, Eisenman, R N
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394680/
https://ncbi.nlm.nih.gov/pubmed/8521822
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